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Erythropoietin in tissue engineering and beyond: a multifunctional macromolecule with emerging roles in organoids, immune modulation, and cancer research
Abstract Erythropoietin (EPO), a glycoprotein hormone conventionally associated with erythropoiesis, has emerged as a versatile macromolecule with substantial therapeutic potential in tissue engineering and regenerative medicine. Beyond its role in red blood cell production, EPO displays pleiotropic effects, including angiogenesis, neuroprotection, anti-apoptosis, immunomodulation, and cell survival, making it a suitable agent for tissue repair and regeneration.
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