Objectives To evaluate the utilisation of oxycodone in a tertiary care centre based in the North of England serving a population of 330?000. Methods A prospective study which gathered data from October 2011 to March 2012. Medical notes were screened to determine the prevalence of oxycodone use during the study period. The medication histories were determined; once the reason for oxycodone initiation was established, it was interpreted and classified as either appropriate or inappropriate.