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Aagosh Kishore Karhale on Muck Rack

Aagosh Kishore Karhale

As seen in: BioRxiv
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Articles

Interferon-γ lowers tumour growth by increasing glycolysis and lactate production in a nitric oxide-dependent manner: implications for cancer immunotherapy

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By Avik Chattopadhyay, Sirisha Jagdish, Aagosh Kishore Karhale, Nikita Ramteke
| BioRxiv
Abstract Interferon-gamma (IFN-γ), the sole member of the type-II interferon family, is well known to protect the host from infectious diseases as well as mount anti-tumour responses. The amounts of IFN-γ in the tumour microenvironment determine the host responses against tumours; however, several tumours employ evasive strategies by responding to low IFN-γ signalling. In this study, the response of various tumour cell lines to IFN-γ was studied in vitro.
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