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Prenatal exposure to perfluoroalkyl substances predicts multimodal brain structural and functional outcomes in children aged 5 years: a birth cohort study
Introduction Polyfluoroalkyl and perfluoroalkyl substances (PFAS) are anthropogenic compounds containing at least one fully fluorinated methyl or methylene carbon atom.1 Because of their amphipathic properties, PFAS have been widely used since the mid-20th century to manufacture products resistant to water, oil, and heat or electrical conductivity.
Human α‐synuclein overexpression upregulates SKOR1 in a rat model of simulated nigrostriatal ageing
AAV adeno-associated viral vector BMP bone morphogenetic protein DA dopaminergic DAT dopamine transporter PD Parkinson's disease RLS restless leg syndrome SKOR1 SKI Family Transcriptional Corepressor 1 SN Substantia nigra TH tyrosine hydroxylase αSyn α-synuclein 1 INTRODUCTION, RESULTS AND DISCUSSION Parkinson's disease (PD) is the fastest-growing neurological disorder (Dorsey et al., 2018; Group, 2017).
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