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Aarren Mannion

As seen in: Nature, BioRxiv
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Articles

The junctional mechanosensor AmotL2 regulates YAP promotor accessibility

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By Aarren Mannion, Honglei Zhao, Yuanyuan Zhang, Ylva von Wright
| BioRxiv
Thank you for your interest in spreading the word about bioRxiv. NOTE: Your email address is requested solely to identify you as the sender of this article. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. Message Subject (Your Name) has forwarded a page to you from bioRxiv Message Body (Your Name) thought you would like to see this page from the bioRxiv website.
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WSB-1 regulates the metastatic potential of hormone receptor negative breast cancer

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By Flore-Anne Poujade, Aarren Mannion, Nicholas Brittain, Andrew Theodosi
| Nature Verified
Metastatic spread is responsible for the majority of cancer-associated deaths. The tumour microenvironment, including hypoxia, is a major driver of metastasis. The aim of this study was to investigate the role of the E3 ligase WSB-1 in breast cancer biology in the context of the hypoxic tumour microenvironment, particularly regarding metastatic spread. In this study, WSB-1 expression was evaluated in breast cancer cell lines and patient samples.
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