Aarushi B. Rathaur on Muck Rack

Aarushi B. Rathaur

As seen in: Nature
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Articles

Developmental CA2 perineuronal net reduction restores social memory in Shank3 mutant mice

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By Emma J. Diethorn, Brayan López, Elizabeth Gould, Aarushi B. Rathaur
| Nature Verified
Abstract Individuals with Autism Spectrum Disorder (ASD) and related neurodevelopmental conditions, like Phelan-McDermid syndrome (PMDS), exhibit social recognition deficits. Shank3B knockout (KO) mice, a genetic model with relevance to ASD and PMDS, have deficits in social recognition in adulthood, but the developmental mechanisms underlying this dysfunction remain unknown.
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