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Articles by Abbi E. Smith
Inhibition of focal adhesion kinase impairs tumor formation and preserves hearing in a murine model of NF2-related schwannomatosis
Abstract NF2 (neurofibromatosis type 2)–related schwannomatosis (NF2-SWN) is a cancer predisposition syndrome characterized by the development of bilateral vestibular (VS) and spinal schwannomas. While benign, these tumors can cause substantial morbidity, and effective pharmacological treatments remain limited. Here, we demonstrate that genetic ablation of focal adhesion kinase (Fak/Ptk2) impairs tumor formation and preserves hearing in a murine model of NF2.
TGFβ-dependent signaling drives tumor growth and aberrant extracellular matrix dynamics in NF1-associated plexiform neurofibroma
Abstract Plexiform neurofibromas (PNFs) are benign tumors of the peripheral nervous system that represent a major source of morbidity in neurofibromatosis type 1 (NF1). A substantial proportion of patients do not respond to current therapies or experience intolerable side effects.
All about cooking rice
Rice is the most popular grain globally, supplying energy, complex carbohydrates, fiber and essential vitamins and minerals. Over half of the worlds population relies on rice as a staple food. Rice is cooked by boiling or steaming and absorbs water while cooking. 1. Combine one cup rice, liquid (see chart below), one teaspoon salt (optional), and one tablespoon butter or margarine (optional) in a two-to three-quart saucepan. 2. Heat to boiling; stir once or twice as it begins to boil.
Healthy summer produce in Indiana
By ABBI SMITH, Extension Educator The Dietary Guidelines for Americans (2020) recommend increasing fruits and vegetables in the U.S. diet. In summertime, you can find fresh fruits and vegetables at farmers markets, roadside stands, and grocery stores across Indiana. Use the following tips to select, prepare, and store these healthy foods. Carrots, greens and tomatoes Select: Look for bright orange carrots with a smooth skin. Try picking medium-sized carrots that taper at the ends.
Improve your brain and body health: The MIND Diet
By ABBI SMITH, Extension Educator Have you heard of The MIND diet? This eating pattern is designed to prevent dementia and loss of brain function as you age. To Read More Subscribe Sign In Continue reading with a subscription Thank you for visiting our website. If you would like to continue reading Putnam County news and sports written by Putnam County people, please click here to learn how you can support community journalism.
Home food preservation resources offered
Home canners are encouraged to join Purdue Extension for the Mastering Home Food Preservation training this summer at the Johnson County Fairgrounds in Franklin. Instructors will teach USDA home food preservation-recommended procedures and provide valuable resources and take-home products for participants. Topics covered throughout the training include food safety, freezing food, boiling water canning, pressure canning, pickling and drying foods and jams and jellies.
Correction: Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 17
See original article: Mund et al. 295 (29): 9948. Julie A. Mund, SuJung Park, Abbi E. Smith, Yongzheng He, Li Jiang, Eric Hawley, Michelle J. Roberson, Dana K. Mitchell, Mohannad Abu-Sultanah, Jin Yuan, Waylan K. Bessler, George Sandusky, Shi Chen, Chi Zhang, Steven D. Rhodes and D. Wade Clapp VOLUME 295 (2020) PAGES 9948–9958 There was an inadvertent typo on the title of this article.
Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 17
Author contributions—J. A. M., S.-J. P., A. E. S., L. J., E. H., D. K. M., J. Y., W. K. B., G. S., S. C., S. D. R., and D. W. C. conceptualization; J. A. M., L. J., E. H., S. C., and D. W. C. resources; J. A. M., S.-J. P., Y. H., L. J., E. H., M. J. R., D. K. M., J. Y., W. K. B., G. S., S. C., C. Z., S. D. R., and D. W. C. data curation; J. A. M., S.-J. P., A. E. S., Y. H., L. J., E. H., M. J. R., D. K. M.J. Y., W. K. B., G. S., S. C., CZ, and D. W. C. formal analysis; J. A. M., S.-J. P., A. E. S., L. J., E. H., D. K. M., W. K. B., G. S., S. C., C. Z., S. D. R., and D. W. C.
Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 1
Author contributions: J.A.M., S.-J.P., A.E.S., L.J., E.H., D.K.M., J.Y., W.K.B., G.S., S.C., S.D.R., and D.W.C. conceptualization; J.A.M., L.J., E.H., S.C., and D.W.C. resources; J.A.M., S.-J.P., Y.H., L.J., E.H., M.J.R., D.K.M., J.Y., W.K.B., G.S., S.C., C.Z., S.D.R., and D.W.C. data curation; J.A.M., S.-J.P., A.E.S., Y.H., L.J., E.H., M.J.R., D.K.M., M.A.-S., J.Y., W.K.B., G.S., S.C., C.Z., and D.W.C. formal analysis; J.A.M., S.-J.P., A.E.S., L.J., E.H., D.K.M., W.K.B., G.S., S.C., C.Z.,...
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