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Abdikani Omar Farah

As seen in: Wiley Online Library, ACS Publications
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Articles

Isothiourea‐Catalysed Acylative Kinetic Resolution of Tertiary Pyrazolone Alcohols

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By Andrew Smith, Matthew Westwood, Abdikani Omar Farah
| Wiley Online Library Verified
Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
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Isothiourea‐Catalysed Acylative Kinetic Resolution of Tertiary Pyrazolone Alcohols

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By Matthew Westwood, Abdikani Omar Farah, Henry Wise, Mike Sinfield
| Wiley Online Library Verified
Introduction Nitrogen-containing heterocyclic compounds are important structural motifs that are ubiquitous in a plethora of biologically relevant compounds which include agrochemicals,1 pharmaceuticals,2 natural products and dyes.3 Their structural significance is readily quantified as 59 % of US FDA approved small-molecule drugs contain a nitrogen heterocycle,4 with these heterocycles commonly incorporated into molecules to improve physicochemical properties.
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Isothiourea‐Catalysed Acylative Dynamic Kinetic Resolution of Tetra‐substituted Morpholinone and Benzoxazinone Lactols

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By Haoxiang Zhu, Alejandro Manchado, Abdikani Omar Farah, Aidan P. McKay
| Wiley Online Library Verified
Introduction Kinetic resolution is a widely developed process that has been extensively used for industrial and academic applications to allow the effective preparation of enantiomerically pure compounds.1 Despite its widespread use, a recognised inherent drawback is that the theoretical maximum yield of a single product enantiomer from a racemate is 50 %.
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