Abdul Samad Rana

Special Issue Published as part of Crystal Growth & Design special issue “Design of Crystals via Crystallization Processes”. 1. Introduction Click to copy section linkSection link copied! Batch cooling crystallization is one of the most common crystallization processes used for the isolation and purification of intermediate and final solid products in the pharmaceutical industry.

4.1. Predicted Flow Fields The predicted liquid flow fields for 100 rpm impeller speed (Run 1 in Table 3 ) on a vertical plane at the 0–180° angular position (see Figure 2 ) are depicted in Figure 5 in the form of velocity vectors. Figure 5 a illustrates the initial liquid mixture flow field at 67 °C before the onset of crystallization, and Figure 5 b is the flow field in the presence of crystals at the end of the crystallization at 20 °C.