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Abdullah Memon

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Articles

Multiomic Selection of Cancer-Testis Antigens as Precision Immuno-oncologic Targets in Head and Neck Cancer

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By Abdullah Memon
| JAMA Network Verified
Key Points Question Can cancer-testis antigens (CTAs) be leveraged as precision immuno-oncologic targets for head and neck cancer? Findings In this cross-sectional study including 33 samples from patients with head and neck squamous cell carcinoma (HNSCC), 23 testis-restricted and 44 testis-selective CTAs with tumor-specific expression were identified in both de novo and radiation-recurrent HNSCCs, validated across transcriptomic, genomic, and proteomic analyses.
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Tumoral Skin Invasion Is an Independent Predictor of Rapid Recurrence in Head and Neck Cancer

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By Abdullah Memon, Mohamed Khalil, Oscar Espinosa, ERIC YANG
| Wiley Online Library Verified
Data Availability Statement The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions.
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Radiation therapy results in preferential tumor antigen-specific lymphodepletion in head and neck cancer - Nature Communications

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By Joseph Zenga, Rachel Kuehn, Angela J. Mathison, Victor X. Jin, Abdullah Memon, Peiman Hematti
| Nature Verified
Abstract Human Papillomavirus (HPV)-negative head and neck squamous cell carcinoma (HNSCC) remains a challenging malignancy, with radiotherapy, alone or combined with immune checkpoint inhibitors, often failing to achieve durable disease control.
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