Abdulsamed KÜKÜRT

3NPA 3-nitropropionic acid CAP capsaicin CNT control CPZ capsazepine cROS cytosolic free reactive oxygen radicals DCFH-DA 2′,7′-dichlorodihydrofluorescein diacetate GSH glutathione GSH-Px glutathione peroxidase HD Huntington's disease LPO lipid peroxidation LSM/800 confocal laser scanning microscope MMD mitochondrial membrane dysfunction mROS mitochondrial free reactive oxygen radicals SIL silymarin TRP transient receptor potential TRPM2 transient receptor potential melastatin 2 TRPV1...

Introduction Endometriosis (EMs) is a prevalent and intricate gynecological ailment characterized by the growth of endometrial-like tissue outside the uterine cavity, such as in the pelvic area, ovaries, and fallopian tubes (1). EMs poses a challenge for 5-10% of reproductive-aged women, often manifesting as pain, dysfertility, and discomfort during intercourse (2).

1 Introduction Endometriosis (EMS) is a common condition in reproductive-age women. Its most common clinical signs are pelvic pain, dyspareunia, a prolonged menstrual period, and a rise in menstrual volume, which can lead to infertility, anxiety, and depression. Ovarian endometriosis (OEM) has the potential to progress to ovarian cancer (1). It is concerning that the etiology of EMS is unclear and has been debated for a long time.