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Abhilasha K. Rani on Muck Rack

Abhilasha K. Rani

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Development of stable, serum-free suspension HEK293T cells for continuous Chikungunya VLPs production

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By Chandra Shekhar Kumar, Manidipa Banerjee, Anurag S. Rathore, Abhilasha K. Rani
| Nature Verified
Abstract Chikungunya Virus (CHIKV) infections occur in over 100 countries. Virus-like particles (VLPs), which replicate the structure of native virus without containing any infectious genome, hold promise as prophylactic vaccines. However, production of CHIK-VLPs using traditional HEK293T adherent cell culture, which relies on use of fetal bovine serum (FBS), faces scalability limitations.
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