Abhir Krishan Nainani

1 Introduction Recurrent respiratory papillomatosis (RRP) is characterised by benign tumours in the respiratory tract due to chronic human papillomavirus (HPV) infection, most commonly types 6 and 11 [1]. Adult-onset RRP, which is usually localised to the larynx, is less common and aggressive, while pulmonary distal dissemination is extremely rare and associated with a worse prognosis [1].

1 Introduction Pulmonary amyloidosis is a rare condition characterised by misfolded proteins that aggregate and deposit in the lungs [1]. It is typically categorised into three subtypes: nodular, diffuse and tracheobronchial amyloidosis (TBA) [1]. TBA occurs in 1% of amyloidosis cases, primarily affecting the central airways, and can lead to obstruction [2].

1 Introduction Neurofibromatosis type-1 is an autosomal dominant disorder due to the loss of the NF1 tumour suppressor gene, leading to increased cell growth and proliferation. The clinical presentation and severity of the disease can vary widely, with diagnosis relying on a range of pathognomonic signs affecting multiple systems [1] (Table 1).