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Abibou Simpore

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Articles

Assessment of microsatellite instability in prostate tissue samples from patients with prostate cancer in Burkina Faso

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By Souleymane Ouattara, Abibou Simpore, Mamadou Traore, Adama Ouattara, Abdou ZOURE, Jacques Simporé, Nafissatou Sanon, Mousso Savadogo, Soayebo Dabré, Marcus Barro, Yasmina Djénéba Rissame, Aïssata Ouédraogo, Bienvenu Désiré Ky, Aristide Fasnewinde Kaboré
| Nature Verified
Abstract A major global public health issue, particularly in sub-Saharan Africa, prostate cancer (PCa) is most often diagnosed at an advanced stage. Data on the molecular mechanisms involved in African populations remain limited. Among the genetic alterations studied, microsatellite instability (MSI) is a marker of genomic instability with diagnostic and therapeutic significance. This preliminary study aimed to assess the frequency and characteristics of MSI in patients with PCa in Burkina Faso.
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