Abril Solis Sigala on Muck Rack

Abril Solis Sigala

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Articles

The endothelial protein C receptor plays an essential role in the maintenance of pregnancy

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By Michelle Castillo, Qiuhui Yang, Abril Solis Sigala, Dosia T. McKinney
| Science Magazine Verified
Abstract Placenta-mediated pregnancy complications are a major challenge in the management of maternal-fetal health. Maternal thrombophilia is a suspected risk factor, but the role of thrombotic processes in these complications has remained unclear. Endothelial protein C receptor (EPCR) is an anticoagulant protein highly expressed in the placenta. EPCR autoantibodies and gene variants are associated with poor pregnancy outcomes.
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