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Adaiah Bavly on Muck Rack

Adaiah Bavly

As seen in: British Journal of Cancer
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Articles

H2A.Z controls the stability and mobility of nucleosomes to regulate expression of the LH genes

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By Sergei Rudnizky, Adaiah Bavly, Omri Malik, Lilach Pnueli
| British Journal of Cancer Verified
To map the occupancy of nucleosomes on Cga and Lhb, we performed quantitative PCR (qPCR) analysis of MNase-digested DNA (MNase-qPCR). We measured occupancy in mature gonadotrope cells (LβT2) that express both genes (Fig. 1a), and in mouse embryonic fibroblasts (MEFs) (Fig. 1b), where the genes are not expressed. Nucleosome occupancy on the Lhb gene in gonadotrope cells shows a well-defined first nucleosome downstream of the TSS region.
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