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Adam C. Bartnik on Muck Rack

Adam C. Bartnik

As seen in: BioRxiv
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Articles

Development of an ultrafast pulsed ponderomotive phase plate for cryo-electron tomography

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By Daniel Du, Adam C. Bartnik, Usama Choudhry, Tanya Tabachnik
| BioRxiv
Abstract Cryo-electron tomography (cryo-ET) is a powerful modality for resolving cellular structures in their native state. While single-particle cryo-electron microscopy (cryo-EM) excels in determining protein structures purified from recombinant or endogenous sources, cryo-ET suffers from low contrast in crowded cellular milieux. A novel experimental approach to enhance contrast in cryo-ET is to manipulate the phase of scattered pulsed electrons using ultrafast pulsed photons.
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