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Addison Barber

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Ultrasound-guided skeletal muscle biopsy technique permits measurement of structural, functional, cellular and biochemical properties

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By Amber Willbanks, Guadalupe Sandoval Meza, Gretchen A. Meyer, Sudarshan Dayanidhi, W. David Arnold, Richard L. Lieber, Ishan Roy, Addison Barber, Jeremie L. A. Ferey
| Nature Verified
Abstract Human muscle biopsies are often required to study or diagnose diseases. However, traditional approaches are challenging due to limited sample size, quality, or participant discomfort. Fine-gauge needle biopsies (≥ 14-gauge), present an alternative but may yield insufficient tissue for comprehensive analysis. Ultrasound guidance, coupled with vacuum-assisted, single needle-insertion multiple sampling addresses these challenges.
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