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Abstract A series of 20 novel polyhydroquinolines (1–20) were synthesized via a simple, efficient and straightforward way of four-component reaction using a one-pot synthetic method in good-to-excellent/high yields. All synthesized compounds were characterized using spectroscopic techniques such ¹H NMR, ¹³C NMR, and High-Resolution Mass Spectrometry (HRMS-ESI+) to confirm their structures.
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