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Adhiraj Goel on Muck Rack

Adhiraj Goel

As seen in: Nature, The Hindu
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Articles

Genome-wide screening reveals producer-cell modifications that improve virus-like particle production and delivery potency

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By Diana Ly, Hyewon Jang, Adhiraj Goel, Arnav Singh, Aditya Raguram
| Nature Verified
Abstract Engineered virus-like particles (eVLPs) are promising vehicles for transient delivery of gene editing agents. While extensive particle engineering has yielded efficient eVLPs, it remains underexplored whether engineering the cells used to produce eVLPs could further improve eVLP properties. We report an unbiased genome-wide screening approach to systematically investigate how genetic perturbations in producer cells influence eVLP production.
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Scientists find ‘hidden’ hormone keeping mice mothers’ bones healthy Original

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By Adhiraj Goel
| The Hindu Verified
Osteoporosis is a condition in which the body’s bones become weak and brittle. There are more than 10 million cases of osteoporosis every year in India, and it disproportionately affects ageing women more than men. The hormone oestrogen plays a crucial role in this condition because it stimulates the growth and formation of new bone. After menopause, the decreased function of ovaries leads to oestrogen being depleted in the body, resulting in the loss of bone mass.
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