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Adina E. Lupu on Muck Rack

Adina E. Lupu

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Articles

Genome-wide mapping of common and rare variant effects on adiposity across childhood

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By Katherine A. Kentistou, Roya Karimi, Lena R. Kaisinger, Robin Hofmeister, Nicolas Fragoso-Bargas, Yajie Zhao, John Tadross, Lukas Steuernagel, Sam Lockhart, Jens C. Brüning, Jimmy Liu, Adrian Cortes, Yancy Lo, Jonathan Davitte, Lieven Clement, Alexandra Havdahl, Ole A. Andreassen, Eirik Bratland, Brian Lam, Stephen O’Rahilly, Giles Yeo, Pål R. Njølstad, Zoltán Kutalik, Felix Day, Marc Vaudel, Ken Ong, Stefan Johansson, Jonas Sundfjord, Adina E. Lupu, Georgina K. C. Dowsett
| Nature Verified
Abstract Our understanding of the genetic architecture of obesity is primarily based on studies of adults, with sparser data from childhood. Here, we conducted age-stratified genetic association studies against objectively measured (n = 62,276) or recalled childhood adiposity-related traits (neff = 599,924), identifying 624 common variants associated with childhood adiposity, with one-third having no concordant association with adult body mass index.
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