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Adithan Kandasamy on Muck Rack

Adithan Kandasamy

As seen in: Nature, PLOS, Science Magazine, BioRxiv
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Articles

Neutrophils exhibit distinct migration phenotypes that are modulated by transendothelial migration

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By Amy Schwartz, Adithan Kandasamy, Yunpeng Tu, Alex De Lecea, Vishal Nigam, Yi-Ting Yeh, Juan C. del Álamo
| Nature Verified
Abstract The extravasation of polymorphonuclear neutrophils (PMNs) is a critical component of the innate immune response that involves transendothelial migration (TEM) and interstitial migration. TEM-mediated interactions between PMNs and vascular endothelial cells (VECs) trigger a cascade of biochemical and mechanobiological signals whose effects on interstitial migration are currently unclear.
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Uncertainty-aware traction force microscopy

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By Adithan Kandasamy, Yi-Ting Yeh, Ricardo Serrano, Mark Mercola
| PLOS
Citation: Kandasamy A, Yeh Y-T, Serrano R, Mercola M, del Alamo JC (2025) Uncertainty-aware traction force microscopy. PLoS Comput Biol 21(6): e1013079. https://doi.org/10.1371/journal.pcbi.1013079 Editor: Daniel A.
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Uncertainty-Aware Traction Force Microscopy

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By Adithan Kandasamy, Yi-Ting Yeh, Ricardo Serrano, Mark Mercola
| BioRxiv
Abstract Traction Force Microscopy (TFM) is a versatile tool to quantify cell-exerted forces by imaging and tracking fiduciary markers embedded in elastic substrates. However, the computations involved in TFM are ill-conditioned, and data smoothing or regularization is required to avoid overfitting the noise in the tracked substrate displacements.
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