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ADAR2 induces the differentiation of osteosarcoma cells by editing activity on IGFBP7: new implications for therapy
Abstract Osteosarcoma is a highly malignant bone tumor which primarily affects the juvenile population and is characterized by high rate of recurrence and metastasis. RNA editing has emerged as a key process in cancer progression. Herein, we investigated the role of RNA editing enzyme ADAR2 (Adenosine Deaminase Acting on RNA 2) in osteosarcoma. We demonstrated that ADAR2 expression increases during osteoblast differentiation and inversely correlates with the aggressiveness of osteosarcoma cells.
[2409.10145] The thermodynamic limit in mean field neural networks
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Journal of Physics A publishes a contemporary programme of special issues guest edited by some of the top practitioners in each field. Special issues are topical collections of high-quality papers from leading experts that are refereed according to the journal's usual exacting standards. For more information, please contact the journal jphysa@ioppublishing.org. Special issue collections Stochastic Resetting: Theory and Applications.
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