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Afroza Aman on Muck Rack

Afroza Aman

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Articles

Endogenous expression and subcellular localization of core apoptosis regulators reveal key differences between embryonic and germline apoptosis in C. elegans

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By Gokul Gopakumar, Stephane Rolland Verified, Anton Gartner, Nadin Memar, Afroza Aman
| Nature Verified
Abstract Apoptosis is a highly conserved form of programmed cell death controlled by a core molecular pathway that was first defined in Caenorhabditis elegans and is conserved in mammals. This pathway is composed of egl-1/BH3-only, ced-9/Bcl-2, ced-4/Apaf-1, and ced-3/Caspase. Despite being discovered more than 20 years ago, tissue-specific apoptosis induction, as well as endogenous expression pattern and dynamic subcellular localization of apoptosis proteins, remain incompletely defined.
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