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Aicha Ait Soussan

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Articles

Routine use of a spike‐in DNA in‐process control for foetal RHD genotyping: Testing the real‐world effectiveness of this ‘canary’

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By Ahmad Javadi, Heleen Woortmeijer, Aicha Ait Soussan
| Wiley Online Library Verified
We evaluated the reliability of a foetal RHD (fRHD) genotyping assay and showed that this was enhanced through a spike-in DNA extraction control. This enhancement in diagnostic accuracy allowed the prevention of four false negative test results. The spike-in control also provided timely detection of reagent-linked performance issues.
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