Aicha R. Mabene

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Integrative multiomic approaches reveal ZMAT3 and p21 as conserved hubs in the p53 tumor suppression network

Sep 18, 2024 |

By Anthony M. Boutelle, David Yao, Haiqing Xu, Aicha R. Mabene

| biorxiv.org

Abstract TP53, the most frequently mutated gene in human cancer, encodes a transcriptional activator that induces myriad downstream target genes. Despite the importance of p53 in tumor suppression, the specific p53 target genes important for tumor suppression remain unclear.

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Aicha R. Mabene

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Integrative multiomic approaches reveal ZMAT3 and p21 as conserved hubs in the p53 tumor suppression network

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