Aiilyan K. Houng on Muck Rack

Aiilyan K. Houng

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Articles

Venous stasis-induced fibrinolysis prevents thrombosis in mice: role of α2-antiplasmin

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By Satish Singh, Aiilyan K. Houng, Guy L. Reed
| Blood Verified
Satish Singh, Aiilyan K. Houng and Guy L. Reed Blood 2019 134:970-978; doi: https://doi.org/10.1182/blood.2019000049 Key Points Venous stasis activates fibrinolysis, which is ineffective because of suppression by α2-antiplasmin. Lack of α2-antiplasmin activity prevents thrombosis, suggesting that it is essential for venous thrombus formation. Abstract Stasis of venous blood triggers deep vein thrombosis by activating coagulation, yet its effects on the fibrinolytic system are not fully understood.
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