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Ailu Yang

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Articles

Chronic HBV Infection Disrupts CCL5-Secreting cNK Cells and Attenuates Liver Accumulation and Activation of DCs and HBV-Specific T Cells

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By Yucan Wang, Yating Yu, Ailu Yang
| Wiley Online Library Verified
1 Introduction Chronic hepatitis B virus (HBV) infection is a global health problem and a major risk factor for the development of liver fibrosis, cirrhosis, and hepatocellular carcinoma [1]. Chronic hepatitis B (CHB) develops due to the complex interactions between HBV and the host immune system, which results in the dysfunction of dendritic cells (DCs), natural killer (NK) cells, and CD8+ T cells [2-5], contributing to liver immune tolerance.
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