Ajeetha Josephrajan on Muck Rack

Ajeetha Josephrajan

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Articles

Unconventional Secretion of Adipocyte Fatty Acid Binding Protein 4 Is Mediated By Autophagic Proteins in a Sirtuin-1-Dependent Manner

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By Ann V Hertzel, Ajeetha Josephrajan, Ellie K. Bohm, Michael W. McBurney
| Diabetes Magazine Verified
Obesity Studies Abstract Fatty acid binding protein 4 (FABP4) is a leaderless lipid carrier protein primarily expressed by adipocytes and macrophages that not only functions intracellularly but is also secreted. The secretion is mediated via unconventional mechanism(s), and in a variety of species, metabolic dysfunction is correlated with elevated circulating FABP4 levels.
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