Ajijur Rahaman

Copper catalyzed C(sp3)–H/C(sp3)–H cross-coupling of arylacetic acid equivalents with methylarenes via α-carbonyl radicals Arylacetic acid equivalents bearing a pyridine group undergo C(sp3)–H/C(sp3)–H cross coupling with diverse methylarenes in the presence of a copper based catalyst system. The reaction proceeds via the formation of α-carbonyl radicals giving access to α,β-diarylpropionic acids.

In Nature, enzymatic reactions proceed through exceptionally ordered transition states giving rise to extraordinary levels of stereoselection. In those reactions, the active site of the enzyme plays crucial roles – through one position, it holds the substrate in the proximity to the reaction epicentre that facilitates both the reactivity and stereoselectivity of the chemical process.

Exploring Amine-rich Supramolecular Silver(I)-Metallogels for Autonomous Self-healing and as Catalysts for Three Component Coupling Reaction A series of Ag(I) supramolecular organo-aqueous gels have been synthesized in presence of an amine-rich triazole ligand as the gelator. Judicious choice of the triazole derivative and counter anion allows a desired spatial orientation of the pendant amine functionality to accentuate the gelation ability and autonomous self-healability via hydrogen bonding.