Akancha Mishra on Muck Rack

Akancha Mishra

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Articles

Plasmodium ARK1 regulates spindle formation during atypical mitosis and forms a divergent chromosomal passenger complex - Nature Communications

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By Ryuji Yanase, Mohammad Zeeshan, David Ferguson, Steven Abel, Sarah L. Pashley, Akancha Mishra, Edward Rea, Declan Brady, Andrew R. Bottrill, Sue Vaughan, Karine Le Roch, David Guttery, Anthony Holder, Eelco C. Tromer, Pushkar Sharma, Rita Tewari, Annu Nagar, Anthonius Eze
| Nature Verified
Abstract Mitosis in Plasmodium spp., the causative agent of malaria, is fundamentally different from model eukaryotes, proceeding via a bipartite microtubule organising centre (MTOC) and lacking canonical regulators such as Polo kinases. During schizogony, asynchronous nuclear replication produces a multinucleate schizont, while rapid male gametogony generates an octaploid nucleus before gamete formation.
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Indian Americans Shine in TIME’s Climate Leaders List

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By Akancha Mishra
| globalindiannewsnetwork.com
TIME magazine’s 100 most influential climate leaders for 2024 includes Indian Americans Ajay Banga, Gaurav Sant, and Sandeep Nijhawan, recognized for their impactful contributions to climate innovation in business. Joining them are Sumant Sinha, founder of India’s ReNew; Madhur Jain, co-founder of Varaha ClimateAg; and London Mayor Sadiq Khan, highlighting global leaders championing climate solutions.
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A novel micronemal protein, Scot1, is essential for apicoplast biogenesis and liver stage development in Plasmodium berghei

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By Ankit Ghosh, Akancha Mishra, Raksha Devi, Sunil Kumar Narwal
| biorxiv.org
Abstract Plasmodium sporozoites invade hepatocytes, transform into liver stages, and replicate into thousands of merozoites that infect erythrocytes and cause malaria. Proteins secreted from micronemes play an essential role in hepatocyte invasion, and unneeded micronemes are subsequently discarded for replication. The liver-stage parasites are potent immunogens that prevent malarial infection.
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