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Intra-articular Delivery of Recombinant Interleukin-1 Receptor Antagonist Protein (Anakinra) Enhances Graft Function in a Porcine Model of Osteochondral Repair - Brendan D. Stoeckl, Rachel A. Flaugh, Akbar N. Syed, Kendall M. Masada, Elizabeth R. Bernstei
Abstract Background: Osteochondral autografts may be subject to suboptimal healing and graft degeneration due to surgical insult and the inflammatory environment of an injured joint. Purpose/Hypothesis: The purpose of this study was to alleviate the negative effect of this inflammatory milieu on the healing of osteochondral grafts by treating operative joints with interleukin-1 receptor antagonist (IL-1ra; Anakinra) in a porcine model.
Morphological Risk Factors for Pediatric Anterior Cruciate Ligament Tears and Tibial Spine Fractures
Get full access to this article View all access and purchase options for this article. References 1. Acevedo RJ, Rivera-Vega A, Miranda G, Micheo W. Anterior cruciate ligament injury: identification of risk factors and prevention strategies. Curr Sports Med Rep. 2014;13(3):186-191. 2. Akcaalan S, Kavaklilar A, Caglar C, et al. Investigation of morphometric factors associated with adolescent ACL rupture. Orthop J Sports Med. 2023;11(9):23259671231194928. 3. Albertson B, Beynnon B, Endres N, Johnson R.
Evaluation of Tibial Slope on Radiographs in Pediatric Patients With Tibial Spine Fractures: An Age- and Sex-Matched Study.
BACKGROUND: A recent study has reported that the radiographic measurement of posterior tibial slope (PTS) is larger in male pediatric patients with tibial spine fractures (TSF) than in controls. However, they found no difference in PTS between female patients and controls. PURPOSE: (1) To identify whether PTS is larger in female pediatric patients with TSF than in female controls and (2) to validate the relationship between PTS and pediatric TSF in male patients.
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