Akhilesh Nandan

Citation: Nandan A, Koseska A (2023) Non-asymptotic transients away from steady states determine cellular responsiveness to dynamic spatial-temporal signals. PLoS Comput Biol 19(8): e1011388. https://doi.org/10.1371/journal.pcbi.1011388 Editor: Attila Csikász-Nagy, Pázmány Péter Catholic University: Pazmany Peter Katolikus Egyetem, HUNGARY Received: February 17, 2023; Accepted: July 25, 2023; Published: August 14, 2023 Copyright: © 2023 Nandan, Koseska.

New Results doi: https://doi.org/10.1101/2023.02.03.526969 Abstract Majority of the theory on cell polarization and the understanding of cellular sensing and responsiveness to localized chemical cues has been based on the idea that non-polarized and polarized cell states can be represented by stable asymptotic switching between them. The existing model classes that describe the dynamics of signaling networks underlying polarization are formulated within the framework of autonomous systems.