Aldona Minecka

1. Introduction Click to copy section linkSection link copied! The pharmaceutical industry is considered to be one of the fastest-growing sectors of the economy. However, despite this, it still struggles with a significant challenge─the poor water solubility (and consequently low bioavailability) of many active substances (APIs)/drugs available on the market, which results in their unsatisfactory therapeutic effect.

1. Introduction Click to copy section linkSection link copied! The pharmaceutical industry is considered to be one of the fastest-growing sectors of the economy. However, despite this, it still struggles with a significant challenge─the poor water solubility (and consequently low bioavailability) of many active substances (APIs)/drugs available on the market, which results in their unsatisfactory therapeutic effect.

Introduction Over the years, the pharmaceutical industry developed a number of approaches that led to the increase of the solubility, dissolution rate, and ultimately bioavailability of poorly water-soluble drugs from solid dosage forms. It turned out that the most common and efficient way to enhance these important properties is the chemical transformation of the active pharmaceutical ingredient (API) into its salt.