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Personalized mapping of body homeostasis using whole-body PET connectomics and routine FDG PET imaging
Abstract Immuno-inflammation and systemic alterations are key features of chronic diseases. While PET molecular imaging is widely used in precision medicine, conventional analyses are lesion-centric, focusing on detection, localization, and quantification. Such approaches overlook disease-induced homeostatic changes occurring at the whole-body level. Recently, PET connectomics has emerged as a graph-based method to characterize metabolic crosstalk between organs.
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