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Aldrin V. Vidal on Muck Rack

Aldrin V. Vidal

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Proximity-driven site-specific cyclization of phage-displayed peptides - Nature Communications

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By Ana Laura Dias, Anna Sigurdardottir, Thomas Murray, Aldrin V. Vidal
| Nature Verified
Abstract Cyclization provides a general strategy for improving the proteolytic stability, cell membrane permeability and target binding affinity of peptides. Insertion of a stable, non-reducible linker into a disulphide bond is a commonly used approach for cyclizing phage-displayed peptides.
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