Alec Barrett

Abstract Neuron-specific morphology and function are fundamentally tied to differences in gene expression across the nervous system. We previously generated a single cell RNA-seq (scRNA-Seq) dataset for every anatomical neuron class in the C. elegans hermaphrodite. Here we present a complementary set of bulk RNA-seq samples for 52 of the 118 canonical neuron classes in C. elegans.

Abstract Alternative splicing is a key mechanism that shapes neuronal transcriptomes, helping to define neuronal identity and modulate function. Here, we present an atlas of alternative splicing across the nervous system of Caenorhabditis elegans. Our analysis identifies novel alternative splicing in key neuronal genes such as unc-40/DCC and sax-3/ROBO.

Brath’s new book showcases visual experiments with text, here using Bertin’s dataset. (Figure 7.14 in the book.) What do a dictionary entry, the Electoral House of Bavaria’s family tree, and Compact Rectangular Euler Diagrams have in common? These are among the dozens of text-based visualizations that you will find in Richard Brath’s new book, Visualizing with Text.