Alejadro Feito on Muck Rack

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Articles

Charged mutations in the FUS low-complexity domain modulate condensate ageing kinetics

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By Eduardo Madroñal Pedraza Verified, Daniel Hoyos, Francisco Gámez, Alejadro Feito
| biorxiv.org
Abstract The assembly of biomolecular condensates is tightly regulated by the intracellular environment. Disruptions in the balance between condensate formation and dissolution—such as irreversible aggregation of low–complexity aromatic–rich kinked segments (LARKS)—have been implicated in multiple neuropathologies.
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