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Articles by Aleksandra Prochera
Enteric glia regulate Paneth cell secretion and intestinal microbial ecology
eLife Assessment This study presents important findings on the function of enteric glia expressing proteolipid protein 1 (PLP1+ glia). The evidence supporting the claims of the authors is solid, although the inclusion of additional data showing the mechanisms by which PLP1+ enteric glia acts on Paneth cells would have strengthened the study. The work will be of interest to colleagues studying intestinal biology.
Enteric glia regulate Paneth cell secretion and intestinal microbial ecology
Abstract Glial cells of the enteric nervous system (ENS) interact closely with the intestinal epithelium and secrete signals that influence epithelial cell proliferation and barrier formation in vitro. Whether these interactions are important in vivo, however, is unclear because previous studies reached conflicting conclusions [1].
Enteric glia regulate Paneth cell secretion and intestinal microbial ecology
Glial cells of the enteric nervous system (ENS) interact closely with the intestinal epithelium and secrete signals that influence epithelial cell proliferation and barrier formation in vitro. Whether these interactions are important in vivo, however, is unclear because previous studies reached conflicting conclusions (Prochera and Rao, 2023).
Could Regenerative Biology Work in Humans?
Mansi Srivastava’s basic research seeks to uncover the origins of whole-body regeneration in animals. Chop a three-banded panther worm in half, and the head and tail will swirl around as if nothing had happened. Even more astonishing, a few days later, the halves will grow to become two complete and almost indistinguishable worms. Loeb associate professor of the natural sciences Mansi Srivastava has studied this process of healing and regeneration for more than a decade.
Virus-mediated inactivation of anti-apoptotic Bcl-2 family members promotes Gasdermin-E-dependent pyroptosis in barrier epithelial cells
Adams K.W. Cooper G.M. Rapid turnover of mcl-1 couples translation to cell survival and apoptosis. J. Biol. Chem. 2007; 282: 6192-6200 Ahmed M. McKenzie M.O. Puckett S. Hojnacki M. Poliquin L. Lyles D.S. Ability of the matrix protein of vesicular stomatitis virus to suppress beta interferon gene expression is genetically correlated with the inhibition of host RNA and protein synthesis. J. Virol. 2003; 77: 4646-4657 Aizawa E. Karasawa T. Watanabe S. Komada T. Kimura H. Kamata R. Ito H. Hishida E. Yamada N.
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