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Keywords Nymphaeales (water lilies) angiosperm evolution aquatic adaptation crop improvement Get full text access Log in, subscribe or purchase for full access. References 1. Project, A.G. ... The Amborella genome and the evolution of flowering plants Science. 2013; 342, 1241089 2. Zhang, L. ... The water lily genome and the early evolution of flowering plants Nature. 2020; 577:79-84 3. Chen, H. ...

Keywords VPS13 XK lipid transfer scramblase cryo-EM molecular dynamics simulations bridge-like lipid-transfer protein membrane contact sites Introduction In eukaryotes, the lipids that constitute organellar membranes are synthesized primarily in the endoplasmic reticulum (ER) before being redistributed to other organelles.

Keywords malaria monoclonal antibodies RIPR vaccines Plasmodium falciparum mAb blood stage Introduction Malaria disease, caused by the parasite Plasmodium falciparum, is a global health problem with an estimated 282 million cases in 2024.1 The WHO currently recommends two malaria vaccines, RTS/S/AS01 and R21/Matrix-M2; however, both vaccines target the same pre-erythrocytic sporozoite stage of the parasite life cycle.

Keywords Th17 IL-23R CHD1 GR EAE phosphoproteomics steroid resistance Introduction CD4+IL-17-producing T helper cells (Th17) that exhibit a nonpathogenic phenotype maintain tissue homeostasis (Th17Hom); however, upon exposure to interleukin 23 (IL-23), they can differentiate into pro-inflammatory Th17 cells (Th17Inf)1,2 that can defend against fungal infections and can also drive autoimmune tissue inflammation.3 IL-23, a member of the IL-12 cytokine family, signals through a heterodimeric...

Keywords brain-spleen axis learned fear olfactory stress Th17 Get full text access Log in, subscribe or purchase for full access. References 1. Leng, L. ∙ Beckers, T. ∙ Vervliet, B. Extinction, avoidance, and generalization: Fear learning processes and their relations with anxious and depressive traits Behav. Res. Ther. 2025; 193, 104841 2. Zhang, T. ∙ Ren, Z. ∙ Wakefield, C.E. ... Are digital psychological interventions for psychological distress and quality of life in cancer patients effective?

Keywords CYP11A1 glucocorticoid TGF-β1 Th17 homeostasis CNS autoimmunity Nrc31 steroid resistance Introduction CD4+ interleukin 17 (IL-17)-producing T helper cells (Th17) are key drivers of autoimmune inflammation, including psoriasis, inflammatory bowel disease (IBD), and multiple sclerosis (MS), yet Th17 cells also mediate homeostatic tissue functions.1 Indeed, two subtypes of Th17 cells exist in both mice and humans.2,3,4,5,6 Homeostatic or non-pathogenic Th17 (Th17Hom) cells maintain...

Main text Gregory J. Hannon passed away in April 2026 at the age of 61. A towering figure in modern molecular biology, Greg influenced remarkably diverse areas of science. His work reshaped our understanding of gene regulation, advanced the discovery of tumor suppressors that regulate the cell-cycle machinery, and uncovered fundamental mechanisms of RNA interference.

Results We trained mice on a simple visuomotor association task.34 Mice were head-fixed in the center of three screens, and they rested their forepaws on a wheel that could be turned leftward or rightward (Figure 1A). To initiate a trial, mice had to hold the wheel still for a randomly selected duration from 0.5 to 2 s. At the beginning of each trial, a static vertical grating was displayed on the right-hand screen, and the position of the stimulus was yoked to the wheel.

Keywords arthropod evolution phylogenomics terrestrialization chemical defenses alkaloids Ordovician comparative genomics tree of life genome sequencing phylogenetics Get full text access Log in, subscribe or purchase for full access. References 2. Brookfield, M.E. ∙ Catlos, E.J. ∙ Suarez, S.E. Vertebrate lies? Arthropods were the first land animals! Geol. Today. 2022; 38:65-68 3. Marek, P.E. ∙ Shear, W.A. Myriapoda Curr. Biol. 2022; 32:R1294-R1296 4. Joly, F.-X. ∙ Coq, S. ∙ Coulis, M. ...

keywords halteres posture inertial sensing flies mechanosensation insect behavio Get full text access Log in, subscribe or purchase for full access. References 1. Massion, J. Postural control system Curr. Opin. Neurobiol. 1994; 4:877-887 2. Cullen, K.E. Sensory signals during active versus passive movement Curr. Opin. Neurobiol. 2004; 14:698-706 3. Tuthill, J.C. ∙ Wilson, R.I. Mechanosensation and Adaptive Motor Control in Insects Curr. Biol. 2016; 26:R1022-R1038 4. Proske, U.