Ales Bartos

Abstract : The volume reduction of the gray matter structures in patients with Alzheimer’s disease is often accompanied by an asymmetric increase in the number of white matter fibers located close to these structures. The present study aims to investigate the white matter structure changes in the motor basal ganglia in Alzheimer’s disease patients compared to healthy controls using diffusion tensor imaging.

Human biological fluids, such as blood plasma, serum or cerebrospinal fluid (CSF), serve as the major biological samples for laboratory and clinical diagnostics. Plasma is the liquid portion of the blood without any blood cells, and serum is the plasma from which clotting proteins, including fibrinogen, have been removed. Serum contains dissolved proteins (albumins, various globulins), electrolytes (Na+, Ca2+, Cl-) and other biologically active compounds (glucose, lipids, hormones) [1].

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