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(A) To track E-SARE activation in CA1 pyramidal cells, we injected a virus from which E-SARE drove dVenus expression and the ePGK housekeeping promoter drove TurboFP635 expression. (B) Timeline of sessions for group 1 (four mice, 12–14 weeks old, 461 ± 103 [SD] cells per mouse, range 344–557557 cells, 1,845 cells total). (C) CA1 neurons’ green/red emission ratios for group 1 mice, relative to each cell’s mean ratio over days 1–3 of imaging (dashed line).
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