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Alex Peter Seabright on Muck Rack

Alex Peter Seabright

As seen in: BioRxiv
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Articles

MuRF1 partners with TRIM72 to impair insulin signalling in skeletal muscle cells

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By Ibrahim Musa, Yusuke Nishimura, Abubakar Audu, Alex Peter Seabright
| BioRxiv
Abstract Muscle RING-finger protein 1 (MuRF1, gene name: TRIM63) is well known as a critical molecular regulator in skeletal muscle atrophy. Despite the identification of several substrates and interaction partners for MuRF1, the precise molecular mechanisms by which MuRF1 causes skeletal muscle atrophy remain unclear.
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