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Articles

BOLD temporal variability differentiates wakefulness from anesthesia-induced unconsciousness

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By Pei-Ching Chang, Alex T. Baria, Maria Virginia Centeno, Mariam E. Ghantous
| American Physiological Society
Even though a number of findings, based on information content or information integration, are shown to define neural underpinnings characteristic of a conscious experience, the neurophysiological mechanism of consciousness is still poorly understood. Here, we investigated the brain activity and functional connectivity changes that occur in the isoflurane anesthetized unconscious state in contrast to the awake-state in rats (awake and/or anesthetized n=68 rats).
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