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Alexander Panetta WASHINGTON on Muck Rack

Alexander Panetta WASHINGTON

As seen in: BioRxiv
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Articles

Cryo-EM Structure of AAV2 Rep68 bound to integration site AAVS1: Insights into the mechanism of DNA melting

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By RAHUL JAISWAL, Vishaka Santosh, Alexander Panetta WASHINGTON, Brandon Braud
| BioRxiv
Abstract The Rep68 protein from Adeno-Associated Virus (AAV) is a multifunctional SF3 helicase that performs most of the DNA transactions required for the viral life cycle. During AAV DNA replication, Rep68 assembles at the origin and catalyzes the DNA melting and nicking reactions during the hairpin rolling replication process to complete the second-strand synthesis of the AAV genome.
Open in Who Shared Issue with article?

In D.C. bar, expats involved in foreign affairs cheer end of Harper era

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By Alexander Panetta WASHINGTON
| The Globe and Mail Verified
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