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Alexandra Keene

As seen in: BioRxiv

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Articles

Sequencing RNA from old, dried specimens reveals past viromes and properties of long-surviving RNA

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By Alexandra Keene, Mark D. Stenglein
| BioRxiv
Abstract Recovery of virus sequences from old samples provides an opportunity to study virus evolution and reconstruct historic virus host interactions. Studies of old virus sequences have mainly relied on DNA or on RNA from fixed or frozen samples. The millions of specimens in natural history museums represent a potential treasure trove of old virus sequences, but it is not clear how well RNA survives in old samples.
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Viral metagenomics of 100-year-old museum specimens highlights the long-term stability of RNA

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By Alexandra Keene, Mark D. Stenglein
| BioRxiv
Abstract Recovery of virus sequences from old samples provides an opportunity to study virus evolution and reconstruct historic virus-host interactions. Studies of old virus sequences have mainly relied on DNA or on RNA from fixed or frozen samples. The millions of specimens in natural history museums represent a potential treasure trove of old virus sequences, but it is not clear how well RNA survives in old samples.
Open in Who Shared Issue with article?
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