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Macrophage-Mediated In Vivo Intracellular Crystallization of Aluminum Oxyhydroxide Adjuvant in Vaccine-Induced Granulomas Click to copy article link Article link copied!
1. Introduction Click to copy section linkSection link copied! Aluminum (Al) is the third most abundant element in the Earth crust, after silicon (Si) and oxygen (O), and is predominantly found in the form of oxide and silicate minerals, such as aluminosilicates. (1−3) In its soluble ionic form (Al3+), Al is toxic to most organisms. Despite its abundance, no essential biological role has been identified for Al in any living organism.
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