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Ali T Abdallah on Muck Rack

Ali T Abdallah

As seen in: Nature, Wiley Online Library, Gut Journal, MDPI, BioRxiv, Zawya, Case Reports in Gastroenterology
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Articles

Oncogenic KRAS-driven type I interferon signalling primes pancreatic cancer for necroptosis

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By Sofya Tishina, Alina Dahlhaus, Marta Manik, Lejla Mulalic, Janine Murr, Michael Kotliar, Hassan Rakhsh-Khorshid, Myrto Kostopoulou, Florian Hocher, Jenny Stroh, Julia Beck, Riley M. Williams, Gülce G. Balta, Fanyu Liu, Ali T Abdallah, Christina M. Bebber, Moritz Reese, Jonathan Lim, Alexander Quaas, Johannes Brägelmann, Manolis Pasparakis, Filippo Beleggia, Siddharth Balachandran, Anna Trauzold, Gianmaria Liccardi, Igor Astsaturov, Maximilian Reichert, Ariadne Androulidaki, Silvia von Karstedt
| Nature Verified
Abstract Pancreatic ductal adenocarcinoma (PDAC) is projected to become the second leading cause of cancer-related death within this decade. Here, we show that its major driver oncogene KRAS activates the cGAS-STING-TBK1 axis, inducing a type I interferon (IFN) response that primes PDAC cells for necroptosis.
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Unraveling Divergent Transcriptomic Profiles: A Comparative Single-Cell RNA Sequencing Study of Epithelium, Gingiva, and Periodontal Ligament Tissues

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By Ali T Abdallah, Anna Konermann
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Revealing Genetic Dynamics: scRNA-seq Unravels Modifications in Human PDL Cells across In Vivo and In Vitro Environments

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By Ali T Abdallah, Michael Peitz, Anna Konermann
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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