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Aliakbar Alizadeh on Muck Rack

Aliakbar Alizadeh

As seen in: Nature, SAGE Publishing, Canadian Journal of Infectious Diseases & Medical Microbiology
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Articles

Preparation and characterization of adapalene and clindamycin-loaded nanofiber for acne treatment

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By Yousef Javadzadeh, Somayeh Hallaj-Nezhadi, Aliakbar Alizadeh, Solmaz Asnaashari, Leila Nouri-Nahand, Khosro Adibkia
| Nature Verified
Abstract Adapalene (ADA) and clindamycin (CLN) are the drugs of choice for the treatment of moderate to severe acne. This study aimed to prepare ADA and CLN nanofibers using polyvinyl pyrrolidone (PVP) and ethyl cellulose (EC) polymers via electrospinning and to investigate their physicochemical properties. In this regard, nanofibers containing ADA, CLN, PVP, and EC were prepared with different polymer ratios.
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Development and in vitro evaluation of glycyrrhetinic acid and alpha-lipoic acid co-loaded nanophytosomes: a strategy to mitigate cisplatin-induced hepatocellular damage

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By Shima Parviz, Negar Azarpira, Aliakbar Alizadeh, Mahsa Sani, Zahra Sherafat, Fatemeh Panahi, Ali Mohammad Tamaddon, Zeinab Zarei-Behjani, Ghazal Farahavar
| Nature Verified
Abstract Cisplatin (CDDP) remains a cornerstone chemotherapeutic agent; however, its clinical use is limited by dose-dependent systemic toxicities, particularly hepatotoxicity mediated by oxidative stress, mitochondrial dysfunction, and inflammatory signaling. Glycyrrhetinic acid (GA) and α-lipoic acid (ALA) provide complementary hepatoprotective mechanisms. Nevertheless, both compounds suffer from poor aqueous solubility, high crystallinity, and limited bioavailability.
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Evaluation of the osteoconductive properties of scaffold containing platete-enriched-fibrin (PRF) with three calcium phosphate (TCP) in the alveolar socket repair after tooth extraction: An animal study - Fatemeh Parsaee, Aliakbar Alizadeh, Mostafa Rezaee

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By Aliakbar Alizadeh, Fatemeh Parsaee, Mostafa Rezaee, Omid Alavi
| SAGE Publishing
Abstract Bone regeneration can be accomplished through osteogenesis, osteoinduction, and osteoconduction mechanisms. This study aimed to investigate the properties of the PRF scaffold with tricalcium phosphate nanoparticles in socket preservation in an animal model. Fabrication of PRF performed. In this experimental study, 18 rats were divided into three negative control, PRF, and PRF/TCP groups.
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