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Evaluation of Levels of Triamcinolone Acetonide in Human Perilymph and Plasma After Intratympanic Application in Patients Receiving Cochlear Implants: A Randomized Clinical Trial | Cochlear Implantation | JAMA Otolaryngology-Head & Neck Surgery | JAMA Net
Key Points Question How much intratympanically injected triamcinolone acetonide diffuses to the perilymph and plasma? Findings In this randomized clinical trial of 40 patients undergoing cochlear implantation, there were similar levels of triamcinolone acetonide in the perilymph 1 hour and 24 hours after injection, and triamcinolone acetonide could be quantified in all analyzed patients at a median (range) level of 796.0 (46.4-7706.7) ng/mL.
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